脂質(zhì)是一類有機(jī)分子,是脂肪酸或其衍生物。脂質(zhì)不溶于水,但溶于有機(jī)溶劑。
脂質(zhì)廣泛用于化妝品和食品工業(yè),脂質(zhì)分子也已成功用于納米顆粒形成和 mRNA 核酸遞送,這導(dǎo)致了兩種疫苗 mRNA-1273 和 BNT162 以及其他臨床批準(zhǔn)藥物的成功。
BroadPharm 提供各種先進(jìn)的脂質(zhì)分子,如可電離脂質(zhì)、陽離子脂質(zhì)、磷脂、PEG 脂質(zhì)、膽固醇等。對我們?nèi)虻目蛻?。我們還
提供新型脂質(zhì)分子的快速定制合成,以增強(qiáng)您在制藥和生物技術(shù)領(lǐng)域的高級研究能力。國內(nèi)客戶可以連續(xù)授權(quán)代理商靶點(diǎn)科技。
Lipids are a class of organic molecules that are fatty acids or their derivatives. Lipids are insoluble in water but soluble in organic solvents.
Lipids are widely used in the cosmetic and food industries, Lipid molecules have also been successfully used in nanoparticle formation and mRNA nucleic acid delivery, which lead to the success of the two vaccines, mRNA-1273 and BNT162 and other clinical approved drugs.
BroadPharm offers a wide array of advanced lipid molecules, such as ionizable lipids, cationic lipids, Phospholipid, PEG lipids, Cholesterol.. to our clients worldwide. We also provide fast- speed custom synthesis of novel lipid molecules to empower your advanced research in the pharmaceutical & biotech field.
脂質(zhì)體(Liposome):納米顆粒的一種亞型,由疏水尾部和親水頭部構(gòu)成磷脂膜。
微球(Microspheres):蛋白質(zhì)或合成聚合物組成,在性質(zhì)上是可生物降解的,理想的粒度在1-1000μm。
膠束(Micelles):由兩親性聚合物自聚集形成的。
微晶(Nanocrystals):改變晶體大小,從而改變藥物體內(nèi)行為。
原位凝膠(Insitugel):進(jìn)入人體之前以溶液形式存在的制劑,但在各種生理條件下會轉(zhuǎn)變?yōu)槟z形式。
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